Microsoft only supports Sysprep.exe usage in IT environments, so don’t expect help outside of internet advice forums if things go wrong. Note that running sysprep.exe doesn’t create a backup or system image, so before playing around with moving drives or swappable images, perform a full backup. Microsoft advises that if you're running Windows 10 and added your Microsoft account and linked it to the digital license on your device, you can use the Activation troubleshooter to reactivate Windows. Significant hardware changes, such as motherboard replacement, might require a call to Microsoft’s activation hotline to resolve.